Nanotechnology

New chemistry study findings have been reported from H. Zhang et al

  2008 NOV 24 - (VerticalNews.com) -- "Hydroxylpropyl-beta-cyclodextrin (HP-beta-CD) was introduced to the surface of magnetic nanoparticles in the presence of NH3 center dot H2O to synthesize magnetic HP-beta-CD composite nanoparticles, which were used as a carrier in magnetic targeted drug delivery. The composite nanoparticles were characterized by FTIR, ICP-AES, TEM and VSM," scientists in Xian, People's Republic of China report.

  "The results showed that the iron content in the composite nanoparticles was 55.4%. The range of size is 10-20 nm and the magnetization is 59.9 emu/g. The capacity of composite nanoparticles for doxorubicin adsorption is 87.8 mu g/mg after incubation for 72 h. The cumulative percentage of released doxorubicin in PBS buffer (pH=7.4) in 1, 4, 10 d were 35.5%, 49.3% and 76.5%, respectively," wrote H. Zhang and colleagues.

  The researchers concluded: "Thus, the magnetic HP-beta-CD composite nanoparticles could be a potential carrier in the magnetic targeted drug delivery."

  Zhang and colleagues published their study in Chinese Journal of Chemistry (Magnetic HP-beta-CD composite nanoparticle: Synthesis, characterization and application as a carrier of doxorubicin in vitro. Chinese Journal of Chemistry, 2008;26(9):1737-1740).

  For additional information, contact M.L. Peng, NW University Xian, Dept. of Chemical, Xian 710069, Shaanxi, People's Republic of China.

  The publisher's contact information for the Chinese Journal of Chemistry is: Wiley-V C H Verlag GmbH, PO Box 10 11 61, D-69451 Weinheim, Germany.

  Keywords: Emerging Technologies, Magnetic Nanoparticles, Nanoparticle, Nanotech, NanotechnologyChemistry.

  This article was prepared by VerticalNews Nanotechnology editors from staff and other reports. Copyright 2008, VerticalNews Nanotechnology via VerticalNews.com.